According to the Centers for Disease Control and Prevention, this is the most common and serious symptom of WNV stimulated by the prevalence of encephalitis. Encephalitis promotes brain tissue inflammation. This causes a pattern of different types of headaches such as migraine, tension, and clusters headaches.
Headaches are a common symptom of various illnesses and health conditions. A journal on the Clinical Manifestations and Outcomes of WNV Infection vol.2 revealed that it can be difficult to trace the presence of WNV through a headache. Headaches can just be caused by anything that can irritate the immune system and they usually fade with time.
This is the major reason why WNV headaches end up becoming severe and increasing the chances of stupor and coma in patients. They are frequently ruled out and left untreated, hence further damage to the patient. In WNV patients, headaches are accompanied by body ache and fatigue.