9. Lymphedema
Another unusual condition that contributes to the inflammation of ankles is lymphedema. This condition refers to the malfunction of lymph nodes. Most patients who have had their lymph nodes removed are prone to lymphedema. The lymphatic system controls the flow of fluid responsible for flushing out viruses, bacteria, and toxins found in the body. This fluid goes through the lymph vessels into the nodes whereby waste is filtered and eventually flushed out of the system.
If the vessels are damaged or lymph nodes removed, the fluid won’t be drained; causing it to accumulate and trigger swelling. There are primary and secondary causes of lymphedema; it can just start without any stimulating factors (primary) or it can be due to other secondary diseases. Underlying causes include lymph node surgery, cancer radiation treatment, and the infection of lymph nodes. If lymphedema is left untreated, it can lead to cancerous deformity of the ankles.